Thermo Scientific™

NHS-Azide

Catalog number: 88902
Thermo Scientific™

NHS-Azide

Catalog number: 88902
Catalog Number
88902
Unit Size
10 mg
Price (USD)
Price: 308.00
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
8890210 mg
Price: 308.00
Your price:
-
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Thermo Scientific NHS-Azide is an amine-reactive compound that can be used to derivatize primary amines of proteins or amine-coated polymer surfaces for ligation to phosphine-modified molecules.

This NHS-ester compound reacts to form covalent bonds with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces). The azide (N3) group reacts with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.

Features of NHS-Azide:

Soluble—reagent easily dissolves in water-miscible solvents for subsequent dilution in aqueous reaction mixtures with cell lysates and other biological samples
Compatible—reaction chemistry occurs effectively in simple buffer conditions; requires no accessory reagents such as copper or reducing agents
Specific—NHS esters are specific for covalent attachment to primary amines (side chain of lysine or N-terminus of polypeptides)
Chemoselective—azide and phosphine groups do not react or interfere with components of biological samples (bioorthogonal) but conjugate to one another with high efficiency

Related Products
NHS-PEG4-Azide
NHS-Phosphine
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine-Phosphine
Cleavable
No
Description
NHS-Azide
Molecular Weight (g/mol)
198.14
PEGylated
No
Spacer Arm Length
2.5 Å
Cell Permeability
Not determined
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
Amine, Azide, NHS Ester
Spacer
Short (<10 Å)
Form
Powder
Quantity
10 mg
Solubility
DMF, DMSO
Format
Standard
Water Soluble
No
Product Type
Crosslinker

Contents & Storage

Upon receipt store at -20°C protected from light and moisture.

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