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Proteintech
PPP3CB Monoclonal Antibody (3C1A3)
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Product Details
66614-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3C1A3
Immunogen
PPP3CB Fusion Protein Ag26987 (365-525 aa encoded by BC028049)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FVGEKVTEM LVNVLSICSD DELMTEGEDQ FDGSAAARKE IIRNKIRAIG KMARVFSVLR EESESVLTLK GLTPTGMLPS GVLAGGRQTL QSATVEAIEA EKAIRGFSPP HRICSFEEAK GLDRINERMP PRKDAVQQDG FNSLNTAHAT ENHGTGNHTA Q (365-525 aa encoded by BC028049)
Target Information
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcineurin A; calcineurin A beta; calcineurin A1; calcineurin A2; Calcineurin subunit A beta; Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CaN Abeta; CNA beta; PP2BA beta; protein phosphatase 3, catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; protein phosphatase-2Bb; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; unnamed protein product
Gene Aliases: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PP2Bbeta; PPP3CB
UniProt ID: (Human) P16298, (Mouse) P48453, (Rat) P20651
Entrez Gene ID: (Pig) 396603, (Human) 5532, (Mouse) 19056, (Rat) 24675
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
hydrolase activity
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
metal ion binding
protein dimerization activity
calcium-dependent protein serine/threonine phosphatase activity
drug binding
protein heterodimerization activity
protein phosphatase
T cell mediated cytotoxicity
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
response to stress
lysosome organization
signal transduction
heart development
learning
memory
regulation of gene expression
dephosphorylation
calcium ion regulated exocytosis
negative regulation of signaling
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
positive regulation of insulin secretion involved in cellular response to glucose stimulus
T cell proliferation
T cell activation
T cell homeostasis
negative regulation of innate immune response
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
axon extension
skeletal muscle fiber development
regulation of insulin secretion
positive regulation of calcineurin-NFAT signaling cascade
calcineurin-mediated signaling
antibacterial innate immune response
negative regulation of protein localization to nucleus
positive regulation of protein localization to nucleus
regulation of synaptic vesicle endocytosis
positive regulation of calcium ion import across plasma membrane
positive regulation of lysosome organization
negative regulation of calcium ion import across plasma membrane
cellular response to drug
positive regulation of NFAT protein import into nucleus
response to amphetamine
social behavior
muscle cell cellular homeostasis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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