Invitrogen™

GAK Recombinant Human Protein

Catalog number:  A30973

Related applications:

Pharma & Biopharma

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Description

This GAK recombinant human protein (1–396) was expressed in insect cells. GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_005246
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Catalytic
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 70.2 kDa
KinaseFamily: NAK Kinase Family
Protein Length: aa 1 - 396
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.