Customize your kinase profiling project to get the right data for your research.
Standard service options include:
- Targets – >490 available biochemical assays
- Mode – Single point concentrations and IC50 and/or EC50 determinations
- Choice of ATP concentration – 10µM, 100µM, and Km [app] ATP (activity assays only)
For the kinases that are available in our activity assays, comprehensive titrations are performed against our panel of available substrates. In addition, ATP titrations are performed for each of these kinases to determine the Km[app] ATP for each target. As a result, you can choose to have your compound run at, above, or below the Km[app] ATP for each kinase within the panel that utilizes an activity assay. This flexibility allows you to identify specific types of inhibitors with various mechanisms of action.
To discuss your kinase profiling project requirements, send us an inquiry