Invitrogen™

MLK4 Recombinant Human Protein

Catalog number:  A30979

Related applications:

Pharma & Biopharma

Back to top

Description

This MLK4 recombinant human protein (114–420) was expressed in insect cells. MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in kidney and pancreas. MLK4 is a negative regulator of TLR4. MLK4 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_115811
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Active, Catalytic
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 60.5 kDa
KinaseFamily: MAP Kinases
Protein Length: aa 114 - 420
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.