Invitrogen™

CDC42 BPG (MRCKG) Recombinant Human Protein

Catalog number:  A32861

Related applications:

Pharma & Biopharma

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Description

This CDC42 BPG (MRCKG) recombinant human protein (1–475) was expressed in insect cells. CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain. CDC42 BPG (MRCKG) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_059995
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Active, Catalytic
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 80.2 kDa
KinaseFamily: Other Kinase Family
Protein Length: aa 1 - 475
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.