Invitrogen™

CDK18/cyclin Y Recombinant Human Protein

Catalog number: A32863
Invitrogen™

CDK18/cyclin Y Recombinant Human Protein

Catalog number: A32863
Catalog Number
A32863
Unit Size
100 µg
Price (USD)
2,115.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
450.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A32863100 µg
2,115.00
Your Price:
***
A333521 mg
6,570.00
Your Price:
***
A3049210 µg
450.00
Your Price:
***
Product Overview
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This CDK18/cyclin Y recombinant human protein (CDK18: full length, cyclin Y: 2–end) was expressed in insect cells. CDK18/cyclin Y serine/threonine kinase or cyclin-dependent kinase 18 belongs to the cdc2/cdkx subfamily of kinases. CDK18/cyclin Y is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2. CDK18/cyclin Y is expressed in a variety of human cell lines and tissues. Elevation in the protein levels of CDK18/cyclin Y in the temporal cortex of Alzheimer's disease relative to control brains has been observed. It is proposed that CDK18/cyclin Y is a paired helical filaments-associated kinase that modulates tau phosphorylation. CDK18/cyclin Y recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
CDK18: AAH11526, CyclinY: NP_659449
Shipping Condition
Dry Ice
Expression System
Insect
Form
Liquid
Protein Form
Recombinant, Active, Catalytic
Species
Human
Validated Application
Kinase Assay
Molecular Weight
80.5/65.5 kDa
Quantity
100 µg
KinaseFamily
CDKs and CHKs
Protein Length
CDK18: Full Length, Cyclin Y: 2 - end
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

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Citations & References