Invitrogen™

MAP2K4 (MEK4) Recombinant Human Protein

Catalog number: A33379
Invitrogen™

MAP2K4 (MEK4) Recombinant Human Protein

Catalog number: A33379
Catalog Number
A33379
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
2,115.00
Your Price:
Availability
***
Quantity
Catalog Number
A30976
also known as A32880
Unit Size
Price (USD)
450.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A333791 mg
6,570.00
Your Price:
***
A32894100 µg
2,115.00
Your Price:
***
A30976
also known as A32880
450.00
Your Price:
***
Product Overview
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Additional Information
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This MAP2K4 (MEK4) recombinant human protein (full length) was expressed in insect cells. MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4. MAP2K4 (MEK4) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_003001
Shipping Condition
Dry Ice
Expression System
Insect
Form
Liquid
Protein Form
Full Length, Recombinant, Active
Species
Human
Validated Application
Kinase Assay
Molecular Weight
70.6 kDa
Quantity
1 mg
KinaseFamily
MAP Kinases
Protein Length
Full Length
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

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Citations & References