This MYO3A (MYO3 alpha) recombinant human protein (1–434) was expressed in insect cells. MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea. MYO3A (MYO3 alpha) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay • Available in multiple pack sizes for convenient use • Also available in our SelectScreen Kinase Profiling Service
For Research Use Only. Not for use in diagnostic procedures.
Recombinant, Active, Catalytic
STE20 Kinase Family
aa 1 - 434
Contents & Storage
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.