Invitrogen™

FGFR3 V555M Recombinant Human Protein

Catalog number:  A33558

Related applications:

Pharma & Biopharma

Back to top

Description

This FGFR3 V555M recombinant human protein (397–end) was expressed in insect cells. FGFR3 receptor tyrosine kinase or Fibroblast growth factor receptor 3 is part of a family of fibroblast growth factor receptors that share similar structure and function. FGFR3 plays a role in several important cellular processes, including regulation of cell growth and division, determination of cell fate, formation of blood vessels, wound healing and embryo development. FGFR3 is involved in the development and maintenance of bone and brain tissue. Mutations in FGFR3 have been implicated in causing bladder cancer, cancer of white blood cells (multiple myeloma) and cervical cancer. FGFR3 V555M recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000133.1
Expression: Insect
Kinase Family: FGF Receptors
Molecular Weight: 71.8 kDa
Product Size: 100 µg
Protein Form: Active,Cytoplasmic,Mutant,Recombinant
Protein Length or Portion (a.a.): aa 397 - end
Protein Tag or Fusion: GST Tag
Shipping Condition: Dry Ice
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol