Invitrogen™

CDK11/cyclin C Recombinant Human Protein

Catalog number:  A33570

Related applications:

Pharma & Biopharma

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Description

This CDK11/cyclin C recombinant human protein (CDK11: 1–502, cyclin C: 1–283) was expressed in insect cells. CDK11/cyclin C serine/threonine kinase is dimeric protein complex. CDK11 is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. Cyclin C is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. CDK11/cyclin C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: CDK11: NP_055891.1, Cyclin C: NP_005181.2
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Active, Catalytic
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 84.9/38.0 kDa
KinaseFamily: CDKs and CHKs
Protein Length: CDK11: 1 - 502, Cyclin C: 1 - 283
Protein Tag: GST Tag, His Tag

Contents & storage

Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol