Invitrogen™

PIP5K1A Recombinant Human Protein

Catalog number: A33577
Invitrogen™

PIP5K1A Recombinant Human Protein

Catalog number: A33577
Catalog Number
A33577
Unit Size
100 µg
Price (USD)
2,115.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
20 µg
Price (USD)
730.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A33577100 µg
2,115.00
Your Price:
***
A3352020 µg
730.00
Your Price:
***
A337401 mg
6,570.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
This PIP5K1A recombinant human protein (full length) was expressed in insect cells. PIP5K1A lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1 is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells. Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphates through 'frizzled' and 'dishevelled', the latter of which directly interacts with and activated PIP5KI. PIP5K1A-mediated PIP(2) production is crucial for HIV-1 entry and the early steps of infection in permissive lymphocytes. Overexpression of wild-type PI4P5K1A increases HIV-1 Env-mediated PIP(2) production and enhances viral replication in primary lymphocytes. PIP5K1A recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Adapta™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
AAH07833
Shipping Condition
Dry Ice
Expression System
Insect
Form
Liquid
Protein Form
Full Length, Recombinant, Active
Species
Human
Validated Application
Kinase Assay
Molecular Weight
82.3 kDa
Quantity
100 µg
KinaseFamily
PI3 Kinase
Protein Length
Full Length
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol

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Citations & References