Invitrogen™

CDK13/cyclin K Recombinant Human Protein

Catalog number:  A33732

Related applications:

Pharma & Biopharma

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Description

This CDK13/cyclin K recombinant human protein (CDK13: 656–1050, cyclin K 1–300) was expressed in insect cells. CDK13/cyclin K serine/threonine kinase is dimeric protein complex. CDK13 is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Cyclin K is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain of the large subunit of RNA polymerase II. CDK13/cyclin K recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: CDK13: NP_003709.3, Cyclin K: NP_001092872.1
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Active, Catalytic
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 73.8/63.0 kDa
KinaseFamily: CDKs and CHKs
Protein Length: CDK13: 656 -1050, Cyclin K: 1 - 300
Protein Tag: GST Tag, His Tag

Contents & storage

Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol