This CDK11/cyclin C recombinant human protein (CDK11: 1–502, cyclin C: 1–283) was expressed in insect cells. CDK11/cyclin C serine/threonine kinase is dimeric protein complex. CDK11 is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. Cyclin C is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. CDK11/cyclin C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay • Available in multiple pack sizes for convenient use • Also available in our SelectScreen Kinase Profiling Service
For Research Use Only. Not for use in diagnostic procedures.
CDK11: NP_055891.1, Cyclin C: NP_005181.2
Recombinant, Active, Catalytic
CDKs and CHKs
CDK11: 1 - 502, Cyclin C: 1 - 283
GST Tag, His Tag
Contents & Storage
Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol