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Bethyl Laboratories
SF3b145/SAP145 Polyclonal Antibody
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FIGURE: 1 / 3
SF3b145/SAP145 Antibody (IHC-00317-T) in IHC (P)
Detection of human SF3b145/SAP145 by IHC-IF. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-SF3b145/SAP145 (Product # IHC-00317) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.
Product Details
IHC-00317-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 775 and 825 of Human splicing factor 3b, subunit 2, 145kDa (spliceosome associated protein 145).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
2.5 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset and Crab-eating macaque
Target Information
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pre-mRNA splicing factor SF3b 145 kDa subunit; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SF3b145; spliceosome associated protein 145; Spliceosome-associated protein 145; Splicing factor 3B subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa; unnamed protein product
Gene Aliases: 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; CFM; Cus1; HFM; SAP145; SF3b1; SF3B145; SF3b150; SF3B2
UniProt ID: (Human) Q13435, (Mouse) Q3UJB0
Entrez Gene ID: (Human) 10992, (Mouse) 319322
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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