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Doxycycline hyclate, Thermo Scientific Chemicals
Catalog number: J60579.22
100 g, Each
Thermo Scientific Chemicals
Doxycycline hyclate, Thermo Scientific Chemicals
Catalog number: J60579.22
100 g, Each
Quantity
Chemical Identifiers
CAS
24390-14-5
IUPAC Name
dihydrogen bis((2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione) ethanol hydrate dichloride
Molecular Formula
C46H58Cl2N4O18
InChI Key
QDDHZFKCHWYXJF-PCLMCNLLSA-N
SMILES
[H+].[H+].O.[Cl-].[Cl-].CCO.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=O)C(=C(N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=O)C(=C(N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12
Specifications
Specification SheetForm
Powder or crystals or crystalline powder
Assay from Suppliers CofA
Report assay (%) or potency (µg/mg)
pH
2.0-3.0
Appearance (Color)
Yellow
Description
Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in the treatment of chlamydia, rickettsia, mycoplasma and some spirochete infections. It is also used to inhibit matrix metalloproteinases at subantimicrobial doses.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Doxycycline hyclate is a broad-spectrum bacteriostatic antibiotic of the tetracycline class
• Doxycycline inhibits bacterial growth by preventing polypeptide formation via inhibition of at least one ribosomal subunit
• Known to reversibly bind the 30S ribosomal subunit and inhibit formation of the aminoacyl-tRNA/mRNA-ribosome complex
• Inhibits matrix metalloproteinases in many microorganisms
Applications
• Effective against the bacteria that cause Lyme disease, chlamydia, rickettsia and mycoplasma; suitable for antibiotic resistance testing and study of cellular mechanisms
• Intended for laboratory use only
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
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