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Milrinone, 98+%, Thermo Scientific Chemicals
Catalog number: J62659.MF
50 mg, Each
Thermo Scientific Chemicals
Milrinone, 98+%, Thermo Scientific Chemicals
Catalog number: J62659.MF
50 mg, Each
Quantity
Catalog number: J62659.MF
also known as J62659-MF
Price (USD)
Price: 610.00
Online price: 527.65
Your price:
Quantity
-
Chemical Identifiers
CAS
78415-72-2
IUPAC Name
2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile
Molecular Formula
C12H9N3O
InChI Key
PZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILES
CC1=C(C=C(C#N)C(=O)N1)C1=CC=NC=C1
Specifications
Specification SheetAppearance (Color)
Pale cream to cream
Residue on ignition
≤0.5%
Form
Powder or crystals or crystalline powder
Loss on Drying
≤1.0%
Assay from Supplier's CofA
≥98.0%
Description
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
Solubility
Soluble in DMSO. Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
Solubility
Soluble in DMSO. Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
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