Coenzyme Q-10, 98+%, Thermo Scientific Chemicals
Coenzyme Q-10, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Coenzyme Q-10, 98+%, Thermo Scientific Chemicals

Component of electron transport chain and in aerobic cellular respiration
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5 g
1 g
25 g
Catalog number J65137.06
Price (USD)/ Each
153.65
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170.00 
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Quantity:
5 g
Request bulk or custom format
Price (USD)/ Each
153.65
Online exclusive
170.00 
Save 16.35 (10%)
Add to cart
Coenzyme Q-10, 98+%, Thermo Scientific Chemicals
Catalog numberJ65137.06
Price (USD)/ Each
153.65
Online exclusive
170.00 
Save 16.35 (10%)
-
Add to cart
Chemical Identifiers
CAS303-98-0
IUPAC Name2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
Molecular FormulaC59H90O4
InChI KeyACTIUHUUMQJHFO-UPTCCGCDSA-N
SMILESCOC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O
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SpecificationsSpecification SheetSpecification Sheet
Assay (unspecified)>98.0%
Residue on ignition<0.1%
Loss on Drying0.04%
It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Solubility
Soluble in chloroform.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Thomas Muller.; Thomas Buttner.; Ali-Farshad Gholipour.; Wilfried Kuhn. Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neuroscience Letters. 2003, 341, (3), 201-204.
  2. Kommuru, T.R.; Gurley, B.; Khan, M.A.; Reddy, I.K. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. International Journal of Pharmaceutics. 2001, 212, (2), 233-246.