Thermo Scientific Chemicals

1-Chloroisoquinoline, 95%, Thermo Scientific Chemicals

Catalog number: L17831.06
5 g, Each
Thermo Scientific Chemicals

1-Chloroisoquinoline, 95%, Thermo Scientific Chemicals

Catalog number: L17831.06
5 g, Each
Quantity
Catalog number: L17831.06
also known as L17831-06
Price (USD)
Price: 127.00
Online price: 109.65
Your price:
Quantity
-

Chemical Identifiers

CAS
19493-44-8
IUPAC Name
1-chloroisoquinoline
Molecular Formula
C9H6ClN
InChI Key
MSQCQINLJMEVNJ-UHFFFAOYSA-N
SMILES
ClC1=C2C=CC=CC2=CC=N1
Form
Crystals or powder or crystalline powder or fused solid
Appearance (Color)
Pale yellow to yellow to orange to brown
Assay (GC)
≥94.0%
Melting Point (clear melt)
27.0-39.0?C

Description

The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.

Solubility
Insoluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

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