'Multidrug resistance protein (MRP) 2 (MRP2; ABCC2), an organic anion transporter apically expressed in liver, kidney, and intestine, plays an important protective role through facilitating the efflux of potentially toxic compounds. We hypothesized that upon a toxic insult, MRP2 is up-regulated in mammalian kidney, thereby protecting the tissue from damage. ... More
The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1.
Continuous regeneration of digestive enzyme (zymogen)-secreting chief cells is a normal aspect of stomach function that is disrupted in precancerous lesions (e.g. metaplasias, chronic atrophy). The cellular and genetic pathways that underlie zymogenic cell (ZC) differentiation are poorly understood. Here, we describe a gene expression analysis of laser capture microdissection ... More
Plasma membrane topology of syncytial domains of herpes simplex virus type 1 glycoprotein K (gK): the UL20 protein enables cell surface localization of gK but not gK-mediated cell-to-cell fusion.
AuthorsFoster TP, Alvarez X, Kousoulas KG
JournalJ Virol
PubMed ID12477855
Most spontaneously occurring mutations that cause extensive herpes simplex virus type 1 (HSV-1)-induced cell fusion are single amino acid changes within glycoprotein K (gK). Despite the strong genetic association of gK with virus-induced cell fusion, its direct involvement in cellular membrane fusion has been controversial, largely due to previously unsuccessful ... More
Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.
Authors
JournalDevelopment
PubMed ID32878924
Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1.
Authors
JournalJ Lipid Res
PubMed ID19767535
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells.
Authors
JournalElife
PubMed ID30188322
Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting.
Authors
JournalJ Clin Invest
PubMed ID24084735
Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.
Authors
JournalDevelopment
PubMed ID34004970
A polysaccharide deacetylase enhances bacterial adhesion in high-ionic-strength environments.
Authors
JournaliScience
PubMed ID34568792
Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish.