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Citations & References (24)
Invitrogen™
Mag-Fluo-4, AM, cell permeant - Special Packaging
The cell-permeant mag-fluo-4, AM is an analog of fluo-4 with a Kd for Mg2+ of 4.7 mM and a KdRead more
| Catalog Number | Quantity |
|---|---|
| M14206 | 10 x 50 μg |
Catalog number M14206
Price (MXN)
-
Quantity:
10 x 50 μg
The cell-permeant mag-fluo-4, AM is an analog of fluo-4 with a Kd for Mg2+ of 4.7 mM and a Kd for Ca2+ of 22 μM, making it useful as an intracellular Mg2+ indicator as well as a low-affinity Ca2+ indicator.
Learn more about ion indicators including calcium, potassium, pH, and membrane potential indicators ›
Learn more about ion indicators including calcium, potassium, pH, and membrane potential indicators ›
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Detection MethodFluorescence
Dye TypeFluorescent Dye-Based
Quantity10 x 50 μg
Shipping ConditionRoom Temperature
For Use With (Application)Cell Viability and Proliferation
For Use With (Equipment)Fluorescence Microscope, Microphotometer, Flow Cytometer
Product TypeMag-Fluo-4 AM
Unit SizeEach
Contents & Storage
Store in freezer -5°C to -30°C and protect from light.
Citations & References (24)
Citations & References
Abstract
Mitochondrial modulation of Ca2+ -induced Ca2+ -release in rat sensory neurons.
Journal:J Neurophysiol
PubMed ID:16760347
'Ca2+ -induced Ca2+ -release (CICR) from ryanodine-sensitive Ca2+ stores provides a mechanism to amplify and propagate a transient increase in intracellular calcium concentration ([Ca2+]i). A subset of rat dorsal root ganglion neurons in culture exhibited regenerative CICR when sensitized by caffeine. [Ca2+]i oscillated in the maintained presence of 5 mM
Rapid functional assays of recombinant IP3 receptors.
Journal:Cell Calcium
PubMed ID:15963563
'Functional assays of inositol 1,4,5-trisphosphate receptors (IP3R) currently use 45Ca2+ release methods, fluorescent Ca2+ indicators within either the ER or cytosol, or electrophysiological analyses of IP3R in the nuclear envelope or artificial bilayers. None of the methods is presently amenable to the rapid, high-throughput quantitative analyses of IP3R function needed
The endoplasmic reticulum: one continuous or several separate Ca(2+) stores?
Journal:Trends Neurosci
PubMed ID:11311379
The Ca2+ store and sink in the endoplasmic reticulum (ER) is important for Ca2+ signal integration and for conveyance of information in spatial and temporal domains. Textbooks regard the ER as one continuous network, but biochemical and biophysical studies revealed apparently discrete ER Ca2+ stores. Recent direct studies of ER
Real-time observations of intracellular Mg2+ signaling and waves in a single living ventricular myocyte cell.
Journal:Anal Chem
PubMed ID:19086893
Despite the important regulatory role of Mg(2+) in metabolic pathways, its underlying mechanism is not completely understood at the single-cell level. This study examined the propagation and dynamics of Mg(2+) signaling across the cell membrane by employing the real-time visualization of intracellular Mg(2+) waves in living ventricular myocytes using a
TRPC channels determine human keratinocyte differentiation: new insight into basal cell carcinoma.
Journal:Cell Calcium
PubMed ID:17920677
Aberrant keratinocyte differentiation is considered to be a key mechanism in the onset of hyperproliferative dermatological diseases, including basal cell carcinoma (BCC). It is, therefore, vital to understand what drives keratinocytes to develop such pathological phenotypes. The role of calcium in keratinocyte differentiation is uncontested but the mechanisms controlling calcium-induced