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Invitrogen
Coronin 1A Monoclonal Antibody (OTI1A5)
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Product Details
MA5-25176
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1A5
Immunogen
Full length human recombinant protein of CORO1A produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding; Clabp coronin; Clipin-A; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein; unnamed protein product
Gene Aliases: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; p57; TACO
UniProt ID: (Human) P31146
Entrez Gene ID: (Human) 11151
immunological synapse formation
phagolysosome assembly
calcium ion transport
vesicle fusion
phagocytosis
actin filament organization
regulation of actin polymerization or depolymerization
regulation of cell shape
epithelial cell migration
cell migration
actin cytoskeleton organization
leukocyte chemotaxis
regulation of actin filament polymerization
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
response to cytokine
nerve growth factor signaling pathway
T cell proliferation
positive regulation of T cell proliferation
T cell activation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive regulation of T cell activation
positive chemotaxis
negative regulation of actin nucleation
negative regulation of cellular component organization
regulation of release of sequestered calcium ion into cytosol
neuron apoptotic process
establishment of localization in cell
early endosome to recycling endosome transport
cellular response to interleukin-4
T cell migration
thymocyte migration
positive regulation of T cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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