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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LQEAWMFYKH TRRKESHAAR RHQRKLLAAI NAFRQVRLKH RKLREQVNSM VDISKMHMIL YDLQQNLSSS HRALEKQIDT LAGKLDALTE LLSTALGPRQ LPEPSQQ
Antigen sequence identity: Mouse 85%; Rat 82%
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Gardos channel; HIK1; hKCa4; IKCa; IKCa1; Intermediate conductance calcium-activated potassium channel protein 4; KCa3.1; KCNN 4; Putative Gardos channel; SKCa 4
Gene Aliases: IK1; IKCA1; KCA4; KCNN4; SK4
Entrez Gene ID: (Human) 3783
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