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The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
DHS2; HIK1; hIKCa1; hKCa4; hSK4; IK; IK1; IKCa; IKCA1; intermediate conductance calcium-activated potassium channel protein 1; intermediate conductance calcium-activated potassium channel protein 4; intermediate conductance K channel; intermediate-conductance Ca-activated K channel; intermediate-conductance calcium-activated potassium channel; KCa3.1; KCA4; KCNN 4; KCNN4; mIKCa1; potassium calcium-activated channel subfamily N member 4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; putative Gardos channel; rKCNN4c; rSK4; SK4; SKCa 4; SKCa4; SKCas; small conductance calcium-activated potassium channel 4
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