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Invitrogen
CEL Polyclonal Antibody
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Product Details
PA5-52504
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CEL. Recombinant protein control fragment (Product #RP-89669).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HWEPYTTENS GYLEITKKMG SSSMKRSLRT NFLRYWTLTY LALPTVTDQE ATPVPPTGDS EATPVPPTGD SG
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 55%.
Target Information
Caboxyl Ester Lipase (CEL), also known as Bile Salt-Activated Lipase, catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. It also has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bile salt-dependent lipase, oncofetal isoform; bucelipase; carboxyl ester hydrolase; carboxyl ester lipase (bile salt-stimulated lipase); cholesterol esterase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; sterol esterase
Gene Aliases: BAL; BSDL; BSSL; CEase; CELL; FAP; FAPP; LIPA; MODY8
Entrez Gene ID: (Human) 1056
lipid metabolic process
triglyceride metabolic process
cholesterol catabolic process
neuron cell-cell adhesion
synapse assembly
fatty acid catabolic process
protein esterification
pancreatic juice secretion
intestinal cholesterol absorption
lipid digestion
intestinal lipid catabolic process
modulation of synaptic transmission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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