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Invitrogen
C19orf48 Polyclonal Antibody
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Product Details
PA5-59814
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C19orf48. Recombinant protein control fragment (Product #RP-99147).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MTVLEAVLEI QAITGSRLLS MVPGPARPPG SCWDPTQCTR TWLLSHTPRR RWISGLPR
Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 40%.
Target Information
The C19orf48 gene, located on chromosome 19q13, encodes a protein involved in various biological processes, including its role as a minor histocompatibility antigen recognized by CD8+ T cells. This gene has been implicated in oncogenesis due to its elevated expression in certain cancer types, such as breast cancer, where it has been associated with poor prognosis. The non-synonymous single-nucleotide polymorphisms within C19orf48 contribute to differential T-cell recognition in donor and recipient cells, highlighting its significance in immune responses. Additionally, C19orf48 has been linked with SNORD88C, a small nucleolar RNA (snoRNA) that guides methylation of rRNA, further illustrating its involvement in cellular proliferation and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: multidrug resistance-related protein
Entrez Gene ID: (Human) 84798
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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