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Invitrogen
HSD17B3 Polyclonal Antibody
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Product Details
PA5-63356
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HSD17B3. Recombinant protein control fragment (Product #RP-103273).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NVGILPNLLP SHFLNAPDEI QSLIHCNITS VVKMTQLILK HMESRQKGLI L
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.
Target Information
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; Estradiol 17-beta-dehydrogenase 2; HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_1; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_2; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_4; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_5; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
Gene Aliases: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058
Entrez Gene ID: (Human) 3293
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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