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Invitrogen
PLCB1 Polyclonal Antibody
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Product Details
PA5-83242
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLCB1. Recombinant protein control fragment (Product #RP-102634).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NKKKSHKSSE GSGKKKLSEQ ASNTYSDSSS MFEPSSPGAG EADTESDDDD DDDDCKKSSM DEGTAGSEAM ATEEMSNLVN
Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphoinositidase C; Phosphoinositide phospholipase C-beta-1; phosphoinositide-specific phospholipase c; phospholipase C, beta 1 (phosphoinositide-specific); Phospholipase C-beta-1; Phospholipase C-I; PLC-154; PLC-beta-1; PLC-I; triphosphoinositide phosphodiesterase
Gene Aliases: EIEE12; KIAA0581; PI-PLC; PLC-154; PLC-beta-1; PLC-I; PLC154; PLCB1; PLCB1A; PLCB1B
UniProt ID: (Human) Q9NQ66
Entrez Gene ID: (Human) 23236
G2/M transition of mitotic cell cycle
signal transduction
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
memory
regulation of G-protein coupled receptor protein signaling pathway
lipid catabolic process
cerebral cortex development
positive regulation of interleukin-12 production
intracellular signal transduction
interleukin-12-mediated signaling pathway
interleukin-15-mediated signaling pathway
positive regulation of embryonic development
positive regulation of GTPase activity
inositol phosphate metabolic process
fat cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
phosphatidylinositol metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of developmental growth
activation of meiosis involved in egg activation
interleukin-1-mediated signaling pathway
regulation of fertilization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of acrosome reaction
negative regulation of monocyte extravasation
positive regulation of CD24 biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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