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Invitrogen
Tartrate Resistant Acid Phosphatase Polyclonal Antibody
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FIGURE: 1 / 3
Tartrate Resistant Acid Phosphatase Antibody (PA5-84356) in IHC (P)
Immunohistochemistry analysis of Tartrate Resistant Acid Phosphatase in human lung and skeletal muscle tissues. Samples were incubated with Tartrate Resistant Acid Phosphatase polyclonal antibody (Product # PA5-84356). Corresponding ACP5 RNA-seq data are presented for the same tissues.
Product Details
PA5-84356
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ACP5. Recombinant protein control fragment (Product #RP-103307).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GGVPNAPFHT AREMANAKEI ARTVQILGAD FILSLGDNFY FTGVQDINDK RFQETFEDVF SDRSLRKVPW YVLAGNHDHL GNVSAQI
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 90%.
Target Information
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
Gene Aliases: ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase
UniProt ID: (Human) P13686
Entrez Gene ID: (Human) 54
ossification
riboflavin metabolic process
negative regulation of cell adhesion
response to zinc ion
dephosphorylation
osteoclast differentiation
positive regulation of cell migration
response to lipopolysaccharide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of tumor necrosis factor production
negative regulation of superoxide anion generation
multicellular organismal response to stress
response to L-ascorbic acid
response to cytokine
negative regulation of nitric oxide biosynthetic process
bone resorption
negative regulation of inflammatory response
defense response to Gram-positive bacterium
bone morphogenesis
response to cholesterol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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