BMP2 Recombinant Human Protein

Catalog number:  PHC7145

Gibco™  Related applications: Cell Viability, Proliferation & Function | Mammalian Cell Culture

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Description

Recombinant Human Bone Morphogenetic Protein 2 (BMP2)is a bioactive protein intended for use in cell culture applications. BMP2is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Bone Morphogenetic Protein 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Bone Morphogenetic Protein 2 (BMP2)specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Research Category: Bone Research, Stem Cell Research
Accession Number: NM001200
Biological Activity: ED50 range = 0.1-1.0 mg⁄mL
Cell Type: Stem Cells
Endotoxin Level: < 0.1 ng/µg
Expression: E. coli
Form: Lyophilized
Gene Aliases: BMP-2, BMP-2, MGC114605, xBMP-2, xbmp2
Gene ID: 548717
Indicator Cell: mouse chondrogenic cell line ATDC5
Mass: 25 µg
Molecular Weight: 26 kDa
Product Line: Gibco®
Product Size: 10 µg
Protein Family: Growth Factors & Receptors
Protein Form: Ligand, Recombinant
Protein Subtype: BMPs (Bone Morphogenetic Proteins) & Related Factors
Purification: Sequential Chromatography
Purity: 95 %
Purity or Quality Grade: Carrier-Free
Reactivity: Human
Species: Human
Specific Activity: 1.0 x 104 - 1.0 x103 units⁄mg
Validated Application: Cell Culture
Shipping Condition: Wet Ice

Contents & storage

Store lyophilized human BMP-2 at 2 to 8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ –20°C. Avoid repeated freeze⁄thaw cycles.

Documents

Manuals & protocols

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