Soluble TNF-RI Recombinant Human Protein

Catalog number: PHR3015

Gibco™  Related applications: Cell Viability, Proliferation & Function | Mammalian Cell Culture

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Recombinant Human Soluble TNF-Receptor Type I (sTNF-RI) is a bioactive protein intended for use in cell culture applications. sTNF-RI is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Soluble TNF-Receptor Type I is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Soluble TNF-Receptor Type I (sTNF-RI) specific activity is determined by measuring the inhibition of TNF-α mediated cytotoxicity in murine L929 cells in the presence of 0.25 ng/ml TNF-α.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.
For Research Use Only. Not for use in diagnostic procedures.


Form: Lyophilized
Mass: 20 µg
Purity: 98 %
Gene ID: 7132
Species: Human
Expression: E. coli
Gene Aliases: Soluble TNF-RI
Product Size: 20 µg
Protein Form: Recombinant, Ligand
Purification: Sequential Chromatography
Protein Family: Cytokines & Receptors
Endotoxin Level: < 0.1 ng/µg
Protein Subtype: TNF (Tumor Necrosis Factor)
Molecular Weight: 18.3 kDa
Research Category: Immunology, Signal Transduction, Oncology, Inflammation
Validated Application: Cell Culture
Shipping Condition: Approved for shipment on Wet or Dry Ice

Contents & storage

Store in freezer (-5 to -30°C).


Manuals & protocols

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