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TGFBR1 (ALK5) Human Protein

Catalog number:  PV5837

Related applications:

Protein Assays and Analysis

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Description

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004603.1
Assay Entry: Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: TKL Group
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen®
Tag Position: N-Terminal
Target Entry: TGFBR1
Target Gene: TGFBR1
Expression System: Baculovirus
Form: Frozen
Protein Family: Kinases & Inhibitors
Protein Form: Full Length
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): TGFBR1
Molecular Weight: 62.9 kDa
Quantity: 10μg
Gene Alias: TGFBR1 (ALK5)
KinaseFamily: STKR Kinase Family
Protein Length: aa 200-503
Protein Tag: GST Tag

Contents & storage

Kinase proteins are shipped on dry ice and should be stored at -80°C.