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TGFBR1 (ALK5) Human Protein

Catalog number: PV5837

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Frozen
Gene ID: TGFBR1
Species: Human
Target Gene: TGFBR1
Gene Aliases: TGFBR1 (ALK5)
Kinase Group: Ser⁄Thr Kinases: TKL Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_004603.1
Molecular Weight: 62.9 kDa
Research Category: Signal Transduction
System Compatibility: LanthaScreen®
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 200-503
Protein Tag or Fusion: GST Tag
Tag Position: N-Terminal
Expression: Baculovirus
Kinase Family: STKR Kinase Family
Protein Form: Full Length
Shipping Condition: Dry Ice

Contents & storage

Kinase proteins are shipped on dry ice and should be stored at -80°C.

Documents

Manuals & protocols