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Highest antigen sequence indentity to the following orthologs: Mouse (69%), Rat (69%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110663. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 81p; pp55; SKAP-55; SKAP55; Src family-associated phosphoprotein 1; Src kinase-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa; unnamed protein product
Gene Aliases: HEL-S-81p; SCAP1; SKAP1; SKAP55
UniProt ID: (Human) Q86WV1
Entrez Gene ID: (Human) 8631
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