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Invitrogen
SKAP55 Polyclonal Antibody
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Product Details
PA5-110663
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human SKAP55. Recombinant protein control fragment (Product #RP-102128).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SLTIPYEEDE EEEEKEETYD DIDGFDSPSC GSQCRPTILP GSVGIKEPTE EKEEEDIYEV LPDEEHDLEE DESGTRRKGV DYASYYQGLW DCHGDQPDEL SFQRGDL
Highest antigen sequence indentity to the following orthologs: Mouse - 69%, Rat - 67%.
Target Information
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 81p; pp55; SKAP-55; SKAP55; Src family-associated phosphoprotein 1; Src kinase-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa; unnamed protein product
Gene Aliases: HEL-S-81p; SCAP1; SKAP1; SKAP55
UniProt ID: (Human) Q86WV1
Entrez Gene ID: (Human) 8631
positive regulation of cell-matrix adhesion
adaptive immune response
immune system process
positive regulation of adaptive immune response
positive regulation of integrin activation
positive regulation of cell-cell adhesion mediated by integrin
positive regulation of heterotypic cell-cell adhesion
positive regulation of cell adhesion
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
protein localization to plasma membrane
positive regulation of leukocyte cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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