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Invitrogen
Human KIAA0391 (aa 27-164) Control Fragment Recombinant Protein
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Product Details
RP-89039
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SYVSLFLADRCGIRNQQRLFSLKTMSPQNTKATNLIAKARYLRKDEGSNKQVYSVPHFFLAGAAKERSQMNSQTEDHALAPVRNTIQLPTQPLNSEEWDKLKEDLKENTGKTSFESWIISQMAGCHSSIDVAKSLLAW
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (57%), Rat (57%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54213. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
KIAA0391, also known as MRPP3 (mitochondrial ribonuclease P protein 3), is a 583 amino acid protein that is located in the mitochondria. KIAA0391 functions in tRNA maturation and is a component of mitochondrial ribonuclease P which cleaves tRNA at the 5'-end. Mitochondrial ribonuclease P is an enzyme composed of RG9MTD1, MRPP22 and KIAA0391 subunits. Due to alternative splicing events, KIAA0391 exists as four isoforms. The gene encoding KIAA0391 maps to human chromosome 14, which contains about 700 genes and makes up about 3. 5% of human cellular DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial ribonuclease P catalytic subunit; Mitochondrial ribonuclease P protein 3; Mitochondrial RNase P protein 3; mitochondrial RNase P subunit 3; Protein only RNase P catalytic subunit; proteinaceous RNase P
Gene Aliases: KIAA0391; MRPP3; PRORP
UniProt ID: (Human) O15091
Entrez Gene ID: (Human) 9692
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