KIAA0391 Proteins

Protein Information

KIAA0391, also known as MRPP3 (mitochondrial ribonuclease P protein 3), is a 583 amino acid protein that is located in the mitochondria. KIAA0391 functions in tRNA maturation and is a component of mitochondrial ribonuclease P which cleaves tRNA at the 5'-end. Mitochondrial ribonuclease P is an enzyme composed of RG9MTD1, MRPP22 and KIAA0391 subunits. Due to alternative splicing events, KIAA0391 exists as four isoforms. The gene encoding KIAA0391 maps to human chromosome 14, which contains about 700 genes and makes up about 3. 5% of human cellular DNA.

Synonyms

1110008L16Rik; KIAA0391; Mitochondrial ribonuclease P catalytic subunit; Mitochondrial ribonuclease P protein 3; mitochondrial RNase P protein 3; mitochondrial RNase P subunit 3; mKIAA0391; MRPP3; Prorp; Protein only RNase P catalytic subunit; proteinaceous RNase P; RGD1305089; RIKEN cDNA 1110008L16 gene; similar to 1110008L16Rik protein