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Zitierungen und Referenzen (7)
Invitrogen™
Alexa Fluor™ 488 Alkyne (Alexa Fluor™ 488 5-Carboxamido-(Propargyl), Bis(Triethylammonium Salt)), 5-isomer
Das grün-fluoreszierende Alexa Fluor® 488-Alkin reagiert über eine kupferkatalysierte Click-Reaktion mit Aziden. Alexa Fluor® 488 ist nicht nur ein sehrWeitere Informationen
| Katalognummer | Menge |
|---|---|
| A10267 | 0,5 mg |
Katalognummer A10267
Preis (EUR)
486,00
Each
Menge:
0,5 mg
Preis (EUR)
486,00
Each
Das grün-fluoreszierende Alexa Fluor® 488-Alkin reagiert über eine kupferkatalysierte Click-Reaktion mit Aziden. Alexa Fluor® 488 ist nicht nur ein sehr heller und lichtbeständiger Fluorophor zum Einsatz in der Durchflusszytometrie, Mikroskopie und HCS, sondern kann auch als bioorthogonales oder biologisch einzigartiges Hapten in Anwendungen mit Signalverstärkung genutzt werden.
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.
Specifications
Chemische ReaktivitätAzid
NachweisverfahrenFluoreszent
FormatFest
Marker oder FarbstoffAlexa Fluor™ 488
Molekulargewicht773,91 Da
ProdukttypAlkyn
Menge0,5 mg
Reaktive GruppeAlkyn
Reaktiver TeilAlkyn
VersandbedingungRaumtemperatur
LöslichkeitDMSO (Dimethylsulfoxid)
FarbeGrün
MarkertypAlexa Fluor Farbstoffe
ProduktlinieAlexa Fluor, Molecular Probes
Unit SizeEach
Inhalt und Lagerung
Bei ≤-20 °C getrocknet und vor Licht geschützt lagern.
Zitierungen und Referenzen (7)
Zitierungen und Referenzen
Abstract
The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules.
Journal:
PubMed ID:24297750
'RNA localization pathways direct numerous mRNAs to distinct subcellular regions and affect many physiological processes. In one such pathway the tumor-suppressor protein adenomatous polyposis coli (APC) targets RNAs to cell protrusions, forming APC-containing ribonucleoprotein complexes (APC-RNPs). Here, we show that APC-RNPs associate with the RNA-binding protein Fus/TLS (fused in sarcoma/translocated
Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells.
Journal:DNA Res
PubMed ID:23649898
'Mouse embryonic stem (ES) cells are prototypical stem cells that remain undifferentiated in culture for long periods, yet maintain the ability to differentiate into essentially all cell types. Previously, we have reported that ES cells oscillate between two distinct states, which can be distinguished by the transient expression of Zscan4
Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites.
Journal:Proc Natl Acad Sci U S A
PubMed ID:21690335
'Signaling from dendritic synapses to the nucleus regulates important aspects of neuronal function, including synaptic plasticity. The neurotrophin brain-derived neurotrophic factor (BDNF) can induce long-lasting strengthening of synapses in vivo and this effect is dependent on transcription. However, the mechanism of signaling to the nucleus is not well understood. Here
Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse formation.
Journal:J Cell Biol
PubMed ID:22201125
'Mammalian Smaug1/Samd4A is a translational repressor. Here we show that Smaug1 forms mRNA-silencing foci located at postsynapses of hippocampal neurons. These structures, which we have named S-foci, are distinct from P-bodies, stress granules, or other neuronal RNA granules hitherto described, and are the first described mRNA-silencing foci specific to neurons.
Click-mediated labeling of bacterial membranes through metabolic modification of the lipopolysaccharide inner core.
Journal:Angew Chem Int Ed Engl
PubMed ID:22323101
Metabolic glycan labeling has recently emerged as a very powerful method for studying cell-surface glycans, which has applications that range from imaging glycans in living multicellular organisms, such as zebrafish or mice, to the identication of metastasis-associaed cell-surface sialoglycoproteins.