Consistone™ Yeast Extract UF

Gibco Consistone Yeast Extract, ultra-filtered (UF), is a functionally defined protein hydrolysate designed for CHO applications. It combines the productivity benefits of traditional peptones with the predictability of chemically defined media, helping teams achieve consistent performance and faster process optimization. With controlled trace-metal levels, Consistone extract supports smoother DoE and scale-up, helping reduce risk, improve reproducibility, and give early-stage development programs the confidence to advance with speed and reliability.

Consistone Yeast Extract UF features include:

• Highly consistent performance with 10–20% lower lot-to-lot variability versus industry benchmarks for more predictable runs and fewer repeats
• Enhanced quality control, including bioburden ≤300 CFU/g and every-lot endotoxin testing ≤500 EU/g
• Proven productivity gains, delivering >20% higher titer vs. TC Yeastolate UF in CHO cells
• Optimized trace-metal ranges for consistent growth, glycosylation, enzyme cofactor control, and stable titer
• Animal origin–free, supporting global regulatory acceptance and helping reduce compliance risk