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Kanamycin monosulfate, Thermo Scientific Chemicals
Katalognummer: J61272.09
10 g, Each
Thermo Scientific Chemicals
Kanamycin monosulfate, Thermo Scientific Chemicals
Katalognummer: J61272.09
10 g, Each
Menge
Katalognummer: J61272.09
auch als J61272-09 bezeichnet
Preis (EUR)
115,20 Online-Preis
128,00
Each
Menge
-
Chemikalien-Kennzeichnungen
CAS
25389-94-0
IUPAC Name
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
Molecular Formula
C18H38N4O15S
InChI Key
OOYGSFOGFJDDHP-KMCOLRRFSA-N
SMILES
OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Spezifikationen
DatenblattOptical Rotation
+112.0 to +123° (c=1, water)
Appearance (Color)
White to cream
Form
Crystals or powder or crystalline powder
Assay from Suppliers CofA
Sulphate, SO₄: ≥15.0 to ≤17.0%
Identification (FTIR)
Conforms
Beschreibung
Antibiotic. Inhibits translocation during protein biosynthesis.Kanamycin monosulfate acts as an antibiotic and used to treat various infections. It is involved in the translation of prokaryotic ribosomes arises due to bacterial cell death. It is used as a selective agent in molecular biology in order to isolate transformants that are expressing a kanamycin resistance gene.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Kanamycin monosulfate is the sulfate salt form of kanamycin A
- It was isolated from Streptomyces kanamyceticus
- This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence
Application
- Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
- This compound is also involved in translating prokaryotic ribosomes
- In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated
RUO – Research Use Only
Abbildungen
Dokumente und Downloads
Zertifikate
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Zitierungen und Referenzen
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Sicherheit und Handhabung
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Respiratory Sensitization
Category 1
Skin Sensitization
Category 1
Reproductive Toxicity
Category 1B
Label Elements
Signal Word
Danger
Hazard Statements
H317 - May cause an allergic skin reaction
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360FD - May damage fertility. May damage the unborn child
Precautionary Statements
P201 - Obtain special instructions before use
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P308 + P313 - IF exposed or concerned: Get medical advice/attention
P342 + P311 - If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician
Additional EU labelling
Restricted to professional users