Search Thermo Fisher Scientific
Elementsuche
StruktursucheThermo Scientific Chemicals
Paclitaxel, 99.5+%, Thermo Scientific Chemicals
Katalognummer: J62734.MC
100 mg, Each
Thermo Scientific Chemicals
Paclitaxel, 99.5+%, Thermo Scientific Chemicals
Katalognummer: J62734.MC
100 mg, Each
Menge
Katalognummer: J62734.MC
auch als J62734-MC bezeichnet
Preis (EUR)
128,70 Online-Preis
143,00
Each
Menge
-
Chemikalien-Kennzeichnungen
CAS
33069-62-4
IUPAC Name
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
Molecular Formula
C47H51NO14
InChI Key
RCINICONZNJXQF-VAZQATRQSA-N
SMILES
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
Spezifikationen
DatenblattAppearance (Color)
White to cream
Assay from Suppliers CofA
≥99.5% (HPLC)
Form
Crystalline powder or granular
Beschreibung
Promotes assembly and inhibits disassembly of microtubules (anti-cancer agent)Paclitaxel is widely used in chemotherapeutic compound. It is used to treat certain types of cancer such as ovarian cancer, breast cancer, lung cancer and pancreatic cancer among others. It interferes with the growth of cancer cells and slows down their growth and spread in the body. It is also used to treat AIDS-related Kaposi's sarcoma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Paclitaxel is a tetracyclic diterpenoid isolated from the Pacific yew, Taxus brevifolia
- Paclitaxel acts as an antineoplastic agent by binding tubulin and preventing cell division
- Paclitaxel may also bind Bcl-2 and lead to disinhibition of apoptosis
Application
- Paclitaxel is used in the study of lung, breast, and ovarian cancers; it may be useful in the research of other cancer types
- It is suitable for cell culture, biochemistry, and molecular biology applications
RUO – Research Use Only
Abbildungen
Dokumente und Downloads
Zertifikate
Nach Chargennummer oder Teil-Chargennummer suchen
Häufig gestellte Fragen (FAQ)
Zitierungen und Referenzen
Search citations by name, author, journal title or abstract text
Sicherheit und Handhabung
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 1
Skin Sensitization
Category 1
Reproductive Toxicity
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Chronic aquatic toxicity
Category 4
Label Elements
Signal Word
Danger
Hazard Statements
H315 - Causes skin irritation
H317 - May cause an allergic skin reaction
H318 - Causes serious eye damage
H335 - May cause respiratory irritation
H361 - Suspected of damaging fertility or the unborn child
H413 - May cause long lasting harmful effects to aquatic life
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician