Thermo Scientific Chemicals

Forskolin, 98+%, Thermo Scientific Chemicals

Katalognummer: J63292.MF
50 mg, Each
Thermo Scientific Chemicals

Forskolin, 98+%, Thermo Scientific Chemicals

Katalognummer: J63292.MF
50 mg, Each
Menge
Informational:Informatorisch:Für diese Chemikalie benötigen wir möglicherweise zusätzliche Informationen für unsere Unterlagen zur behördlichen und chemischen Konformität. Falls erforderlich, setzen wir uns mit Ihnen in Verbindung, sobald Ihre Bestellung eingegangen ist, um diese Informationen zu erfragen.
Katalognummer: J63292.MF
auch als J63292-MF bezeichnet
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Chemikalien-Kennzeichnungen

CAS
66575-29-9
IUPAC Name
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
Molecular Formula
C22H34O7
InChI Key
OHCQJHSOBUTRHG-KGGHGJDLSA-N
SMILES
CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
Appearance (Color)
White
Assay from Supplier's CofA
≥98.0% (HPLC)
Form
Powder
Proton NMR
Conforms to structure

Beschreibung

Forskolin acts as an adenylyl cyclase activator. It is used in the treatment of hypertension, asthma, eczema, psoriasis, congestive heart failure, angina, stomachache, gastric and intestinal spasm. It also plays an important role in the treatment of rheumatism, heart, blood and circulation conditions and cancers. It is used to induce menstruation and as an oral contraceptive.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite

• It is a protein kinase A agonist and a cyclic ketone • Forskolin is an antihypertensive and muscle relaxant; it can also promote the release of pituitary hormones and prevent platelet aggregation

Application

• Forskolin assists in neuron differentiation in vitro

• Useful for studies of cell metabolism and development; there is some evidence of its usefulness in the study of glaucoma

• It is intended for cell culture and biochemistry applications

RUO – Research Use Only

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    Sicherheit und Handhabung


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute dermal toxicity
    Category 4
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H312 - Harmful in contact with skin

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water