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Thermo Scientific Chemicals

G418 disulfate, 50mg/ml solution, Thermo Scientific Chemicals

Katalognummer: J63871.AB
10 mL, Each
G418 disulfate, 50mg/ml solution, Thermo Scientific Chemicals
G418 disulfate, 50mg/ml solution, Thermo Scientific Chemicals
G418 disulfate, 50mg/ml solution, Thermo Scientific Chemicals
Zertifikate
Thermo Scientific Chemicals

G418 disulfate, 50mg/ml solution, Thermo Scientific Chemicals

Katalognummer: J63871.AB
10 mL, Each
Menge
Zertifikate
Informational:Informatorisch:Für diese Chemikalie benötigen wir möglicherweise zusätzliche Informationen für unsere Unterlagen zur behördlichen und chemischen Konformität. Falls erforderlich, setzen wir uns mit Ihnen in Verbindung, sobald Ihre Bestellung eingegangen ist, um diese Informationen zu erfragen.
Katalognummer: J63871.AB
auch als J63871-AB bezeichnet
Preis (EUR)
97,20 Online-Preis
108,00
Each
Menge
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Chemikalien-Kennzeichnungen

CAS
108321-42-2
IUPAC Name
(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-2-(1-hydroxyethyl)oxane-3,4-diol; bis(sulfuric acid)
Molecular Formula
C20H44N4O18S2
InChI Key
UHEPSJJJMTWUCP-KETIWVBHNA-N
SMILES
OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O

Spezifikationen

DatenblattDatenblatt
Appearance (Color)
Clear colorless
Absorbance
A570 nm: ≤0.10
Potency
≥700 µg/mg
Form
Liquid
Absorbance
at 280 nm: ≤0.015

Beschreibung

G418 disulfate is used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene. Optimal concentrations for selection and maintenance vary by cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• G418 sulfate (geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea
• G418 is bacteriostatic that prevents polypeptide formation by inhibiting the elongation step of polypeptide synthesis
Applications
• G418 sulfate can be used for the selection of genetically engineered cells in both eukaryotes and prokaryotes
• Laboratory-grade for applications such as biochemistry
RUO – Research Use Only

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    Sicherheit und Handhabung


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Respiratory Sensitization
    Category 1
    Skin Sensitization
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H317 - May cause an allergic skin reaction

    H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing

    P285 - In case of inadequate ventilation wear respiratory protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention

    P342 + P311 - If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician