Thermo Scientific Chemicals

N-Acetyl-Ser-Asp-Lys-Pro

Katalognummer: J66430.LB0
5mg, Each
Thermo Scientific Chemicals

N-Acetyl-Ser-Asp-Lys-Pro

Katalognummer: J66430.LB0
5mg, Each
Menge
Katalognummer: J66430.LB0
auch als J66430-#0 bezeichnet
Preis (EUR)
Menge
-

Chemikalien-Kennzeichnungen

CAS
127103-11-1
IUPAC Name
1-{6-amino-2-[3-carboxy-2-(2-acetamido-3-hydroxypropanamido)propanamido]hexanoyl}pyrrolidine-2-carboxylic acid
Molecular Formula
C20H33N5O9
InChI Key
HJDRXEQUFWLOGJ-UHFFFAOYNA-N
SMILES
CC(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(O)=O
Appearance (Color)
White
Purity
≥94.0%
Molecular Weight
Consistent (Theoretical: 487.5)
Form
Lyophilized Powder

Beschreibung

N-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin converting enzyme, which is responsible for its degradation in vivo.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
N-Acetyl-Ser-Asp-Lys-Pro hemmt den Eintritt pluripotenter hämatopoetischer Stammzellen in die S-Phase des Zellzyklus und schützt bei Mäusen vor Ara-C-Letalität. Ist ein spezifisches Substrat für das N-terminale aktive Zentrum von Angiotensin.
RUO – Research Use Only

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