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Zitierungen und Referenzen (6)
Invitrogen™
QSY™ 21 Carboxylic Acid, Succinimidyl Ester
Der aminreaktive Quencher QSY™ 21 Succinimidylester verfügt über eine breite und intensive Absorption (maximal ∼661 nm), aber keine Fluoreszenz, wodurchWeitere Informationen
| Katalognummer | Menge |
|---|---|
| Q20132 | 5 mg |
Katalognummer Q20132
Preis (EUR)
394,65
Online Exclusive
526,00Ersparnis 131,35 (25%)
Each
Menge:
5 mg
Preis (EUR)
394,65
Online Exclusive
526,00Ersparnis 131,35 (25%)
Each
Der aminreaktive Quencher QSY™ 21 Succinimidylester verfügt über eine breite und intensive Absorption (maximal ∼661 nm), aber keine Fluoreszenz, wodurch er als Akzeptor für Fluoreszenz-Resonanzenergietransfer (FRET)-Anwendungen einsetzbar ist.
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.
Specifications
Chemische ReaktivitätAmin
Marker oder FarbstoffQSY™ 21
ProdukttypSuccinimidyll-Ester
Menge5 mg
Reaktiver TeilAktiv-Ester, Succinimidylester
VersandbedingungNasseis
MarkertypQuencher-Farbstoffe
ProduktlinieQSY
Unit SizeEach
Inhalt und Lagerung
Bei -5 bis -30 °C lagern und vor Licht schützen.
Zitierungen und Referenzen (6)
Zitierungen und Referenzen
Abstract
Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice.
Journal:Proc Natl Acad Sci U S A
PubMed ID:20566877
'The slow growth rate and genetic intractability of tubercle bacilli has hindered progress toward understanding tuberculosis, one of the most frequent causes of death worldwide. We overcame this roadblock through development of near-infrared (NIR) fluorogenic substrates for beta-lactamase, an enzyme expressed by tubercle bacilli, but not by their eukaryotic hosts,
An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging.
Journal:Bioconjug Chem
PubMed ID:19331388
'Apoptosis is required for normal cellular homeostasis, and deregulation of the apoptotic process is implicated in various diseases. Previously, we developed a cell-penetrating near-infrared fluorescence (NIRF) probe based on an activatable strategy to detect apoptosis-associated caspase activity in vivo. This probe consisted of a cell-penetrating Tat peptide conjugated to an
Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin
Journal:Bioconjug Chem
PubMed ID:19072537
In vivo molecular cancer imaging with monoclonal antibodies has great potential not only for cancer detection, but also for cancer characterization. However, the prolonged retention of intravenously injected antibody in the blood causes low target tumor-to-background ratio (TBR). Avidin has been used as a
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.
Journal:Nat Chem Biol
PubMed ID:17828252
We have generated a series of quenched near-infrared fluorescent activity-based probes (qNIRF-ABPs) that covalently target the papain-family cysteine proteases shown previously to be important in multiple stages of tumorigenesis. These 'smart' probes emit a fluorescent signal only after covalently modifying a specific protease target. After intravenous injection of NIRF-ABPs into
Time-resolved Förster-resonance-energy-transfer DNA assay on an active CMOS microarray.
Journal:Biosens Bioelectron
PubMed ID:18515059
We present an active oligonucleotide microarray platform for time-resolved Förster-resonance-energy-transfer (TR-FRET) assays. In these assays, immobilized probe is labeled with a donor fluorophore and analyte target is labeled with a fluorescence quencher. Changes in the fluorescence decay lifetime of the donor are measured to determine the extent of hybridization. In