Search
인용 및 참조 문헌 (2)
Thermo Scientific™
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| 22363 | 50 mg |
카탈로그 번호 22363
제품 가격(KRW)
324,000
온라인 행사
Ends: 31-Mar-2026
381,000할인액 57,000 (15%)
Each
수량:
50 mg
제품 가격(KRW)
324,000
온라인 행사
Ends: 31-Mar-2026
381,000할인액 57,000 (15%)
Each
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).
Features of SMPH:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
Features of SMPH:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성Yes
설명SMPH
형태Solid
라벨링 방법Chemical Labeling
분자량379.36
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, NHS Ester
배송 조건Ambient
용해도DMF, DMSO
스페이서 암 길이14.2 Å
수용성No
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Medium (10 to 30 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))?
인용 및 참조 문헌 (2)
인용 및 참조 문헌
Abstract
Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy.
Journal:J Exp Med
PubMed ID:19667059
Allergen-specific desensitization is the only disease-modifying therapy currently available for the treatment of allergies. These therapies require application of allergen over several years and some may induce life-threatening anaphylactic reactions. An ideal vaccine for desensitization should be highly immunogenic and should alleviate allergic symptoms upon few injections while being nonreactogenic.
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Journal:J Biol Chem
PubMed ID:12972413
Heterobifunctional thiol to amine cross-linking agents were used to gain new insights on the dynamics and conformational factors governing the interaction between the cardiac Ca2+ pump (SERCA2a) and phospholamban (PLB). PLB is a small protein inhibitor of SERCA2a that reduces enzyme affinity for Ca2+ and thereby regulates cardiac contractility. We