Thermo Scientific™

SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

Catalog number: 22363
Thermo Scientific™

SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

Catalog number: 22363
Catalog Number
22363
Unit Size
50 mg
Price (USD)
Price: 245.00
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
2236350 mg
Price: 245.00
Your price:
-
Product Overview
Figures
Videos
Recommendations
Recommendations
Documents
FAQ
Citations & References
Additional Information
Recommendations
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).

Features of SMPH:

Reactive groups: NHS ester and maleimide
Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine-Sulfhydryl
Cleavable
No
Description
SMPH
Molecular Weight (g/mol)
379.36
PEGylated
No
Spacer Arm Length
14.2 Å
Cell Permeability
Yes
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
Maleimide, NHS Ester
Spacer
Medium (10 to 30 Å)
Form
Solid
Quantity
50 mg
Solubility
DMF, DMSO
Format
Standard
Water Soluble
No
Product Type
Crosslinker

Contents & Storage

Upon receipt store desiccated at 4°C.

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text