Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester)
Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester)
Citas y referencias (5)
Thermo Scientific™

Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester)

Thermo Scientific Pierce Sulfo-GMBS es un entrecruzador de amina a sulfhidrilo soluble en agua que contiene grupos reactivos de ésterMás información
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Número de catálogoCantidad
2232450 mg
Número de catálogo 22324
Precio (MXN)
-
Cantidad:
50 mg
Thermo Scientific Pierce Sulfo-GMBS es un entrecruzador de amina a sulfhidrilo soluble en agua que contiene grupos reactivos de éster NHS y maleimida en extremos opuestos de un brazo espaciador corto (7,3 angstroms).

Características de Sulfo-GMBS:

• Grupos reactivos: Éster sulfo-NHS y maleimida
• Reactivo hacia: grupos amino y sulfhidrilo
• No escindible
• Soluble en agua (en comparación con GMBS)
• Tiene un bajo potencial para obtener una respuesta inmunitaria del entrecruzador, lo que asegura que la respuesta primaria al conjugado de proteína portadora de antígeno no se diluya mediante una respuesta contra un determinante en el entrecruzador
• GMBS y Sulfo-GMBS son conocidos por ser menos inmunogénicos que SMCC

Referencias del producto:

Guía de aplicación entrecruzada: búsqueda de referencias literarias recientes para este producto

Productos relacionados
GMBS (N-γ-maleimidobutirilo-oxysuccinimida éster)
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Permeabilidad celularNo
DescripciónSulfo-GMBS
FormularioPolvo
Método de etiquetadoEtiqueta química
Peso molecular382.28
PegiladoNo
Línea de productosPierce
Cantidad50 mg
Fracción reactivaMaleimida, éster Sulfo-NHS
Condiciones de envíoAmbiente
SolubilidadAgua
Longitud del brazo del separador7,3 Å
Soluble en aguaSí
Reactividad químicaAmino-sulfhidrilo
CleavableNo
Tipo de enlace cruzadoHeterobifuncionales
FormatoEstándar
Tipo de productoEntrecruzador
SeparadorCorto (< 10 Å)
Unit SizeEach
Contenido y almacenamiento
Tras su recepción, almacenar desecado a -20 °C.

Preguntas frecuentes

Can you provide the shelf-life for Sulfo-GMBS (N-&gamma;-maleimidobutyryl-oxysulfosuccinimide ester)?

Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

Citations & References (5)

Citations & References
Abstract
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms.
Authors:Adessi C, Matton G, Ayala G, Turcatti G, Mermod JJ, Mayer P, Kawashima E
Journal:Nucleic Acids Res
PubMed ID:11024189
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides ... More
Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway.
Authors:Weber AN, Moncrieffe MC, Gangloff M, Imler JL, Gay NJ
Journal:J Biol Chem
PubMed ID:15795223
In Drosophila, the signaling pathway mediated by the Toll receptor is critical for the establishment of embryonic dorso-ventral pattern and for innate immune responses to bacterial and fungal pathogens. Toll is activated by high affinity binding of the cytokine Spätzle, a dimeric ligand of the cystine knot family. In vertebrates, ... More
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A.
Authors:Sheridan JT, Worthington EN, Yu K, Gabriel SE, Hartzell HC, Tarran R
Journal:J Biol Chem
PubMed ID:21056985
Members of the Anoctamin (Ano)/TMEM16A family have recently been identified as essential subunits of the Ca(2+)-activated chloride channel (CaCC). For example, Ano1 is highly expressed in multiple tissues including airway epithelia, where it acts as an apical conduit for transepithelial Cl(-) secretion and helps regulate lung liquid homeostasis and mucus ... More
Studying the protein organization of the postsynaptic density by a novel solid phase- and chemical cross-linking-based technology.
Authors:Liu SH, Cheng HH, Huang SY, Yiu PC, Chang YC
Journal:Mol Cell Proteomics
PubMed ID:16501281
Agarose beads carrying a cleavable, fluorescent, and photoreactive cross-linking reagent on the surface were synthesized and used to selectively pull out the proteins lining the surface of supramolecules. A quantitative comparison of the abundances of various proteins in the sample pulled out by the beads from supramolecules with their original ... More
Rat liver carnitine palmitoyltransferase 1 forms an oligomeric complex within the outer mitochondrial membrane.
Authors:Faye A, Esnous C, Price NT, Onfray MA, Girard J, Prip-Buus C
Journal:J Biol Chem
PubMed ID:17650509
Carnitine palmitoyltransferase (CPT) 1A catalyzes the rate-limiting step in the transport of long chain acyl-CoAs from cytoplasm to the mitochondrial matrix by converting them to acylcarnitines. Located within the outer mitochondrial membrane, CPT1A activity is inhibited by malonyl-CoA, its allosteric inhibitor. In this study, we investigate for the first time ... More