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引用資料與參考文獻 (3)
Thermo Scientific™
BMOE (bismaleimidoethane)
Thermo Scientific Pierce BMOE is a short-arm, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide深入閱讀
| 產品號碼 | Quantity |
|---|---|
| 22323 | 50 mg |
產品號碼 22323
價格 (TWD)
5,500.00
Online offer
Ends: 31-Dec-2025
7,840.00您節省 2,340.00 (30%)
Each
Quantity:
50 mg
價格 (TWD)
5,500.00
Online offer
Ends: 31-Dec-2025
7,840.00您節省 2,340.00 (30%)
Each
Thermo Scientific Pierce BMOE is a short-arm, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide cysteines).
Features of BMOE:
• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Short (8.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 7-atom spacer arm
• Shortest bismaleimide crosslinker available for close proximity crosslinking
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
Related Products
BMB (1,4-bismaleimidobutane)
BMH (bismaleimidohexane)
BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
Features of BMOE:
• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Short (8.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 7-atom spacer arm
• Shortest bismaleimide crosslinker available for close proximity crosslinking
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
Related Products
BMB (1,4-bismaleimidobutane)
BMH (bismaleimidohexane)
BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
For Research Use Only. Not for use in diagnostic procedures.
規格
Cell PermeabilityYes
DescriptionBMOE
FormSolid
Labeling MethodChemical Labeling
Molecular Weight (g/mol)220.18
PEGylatedNo
Product LinePierce
Quantity50 mg
Reactive MoietyMaleimide
Shipping ConditionAmbient
SolubilityDMF, DMSO
Spacer Arm Length8.0 Å
Water SolubleNo
Chemical ReactivitySulfhydryl-Sulfhydryl
CleavableNo
Crosslinker TypeHomobifunctional
FormatStandard
Product TypeCrosslinker
SpacerShort (<10 Å)
Unit SizeEach
內容物與存放
Upon receipt store at 4°C.
常見問答集 (常見問題)
Can you provide the shelf-life for BMOE (bismaleimidoethane)?
引用資料與參考文獻 (3)
引用資料與參考文獻
Abstract
Structure-based analysis of VDAC1 protein: defining oligomer contact sites.
Journal:J Biol Chem
PubMed ID:22117062
'The outer mitochondrial membrane protein, the voltage-dependent anion channel (VDAC), is increasingly implicated in the control of apoptosis. Oligomeric assembly of VDAC1 was shown to be coupled to apoptosis induction, with oligomerization increasing substantially upon apoptosis induction and inhibited by apoptosis blockers. In this study, structure- and computation-based selection of
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis.
Journal:J Cell Biol
PubMed ID:18166653
During protein integration into the endoplasmic reticulum, the N-terminal domain preceding the type I signal-anchor sequence is translocated through a translocon. By fusing a streptavidin-binding peptide tag to the N terminus, we created integration intermediates of multispanning membrane proteins. In a cell-free system, N-terminal domain (N-domain) translocation was arrested by
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.
Journal:Proc Natl Acad Sci U S A
PubMed ID:21098299
Amyotrophic lateral sclerosis (ALS) is a disorder characterized by the death of both upper and lower motor neurons and by 3- to 5-yr median survival postdiagnosis. The only US Food and Drug Administration-approved drug for the treatment of ALS, Riluzole, has at best, moderate effect on patient survival and quality