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Bethyl Laboratories
DIXDC1 Polyclonal Antibody
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FIGURE: 1 / 1
DIXDC1 Antibody (A304-116A) in IP
Detection of human DIXDC1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-DIXDC1 antibody (Product # A304-116A) (lot 1) used for IP at 6 µg/mg lysate. DIXDC1 was also immunoprecipitated by rabbit anti-DIXDC1 antibodies A304-117A, A304-118A and A304-119A. For blotting immunoprecipitated DIXDC1, A304-119A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A304-116A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 100 to 150 of human DIX Domain Containing 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding protein; DIXDC1L; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin; unnamed protein product
Gene Aliases: CCD1; DIXDC1; KIAA1735
UniProt ID: (Human) Q155Q3
Entrez Gene ID: (Human) 85458
Wnt signaling pathway
cerebral cortex cell migration
cerebral cortex radially oriented cell migration
cell proliferation in forebrain
forebrain ventricular zone progenitor cell division
positive regulation of Wnt signaling pathway
regulation of actin cytoskeleton organization
negative regulation of neuron differentiation
canonical Wnt signaling pathway
regulation of microtubule cytoskeleton organization
modification of postsynaptic actin cytoskeleton
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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