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Bethyl Laboratories
UMPS Polyclonal Antibody
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FIGURE: 1 / 2
UMPS Antibody (A304-258A) in WB
Detection of human and mouse UMPS by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-UMPS antibody (Product # A304-258A) (lot A304-258A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A304-258A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 430 to 480 of Human Uridine Monophosphate Synthetase.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OMPdecase; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-monophosphate decarboxylase (EC 4.1.1.23); orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; unnamed protein product; Uridine 5'-monophosphate synthase
Gene Aliases: 1700095D23Rik; AA408257; AL033308; BB164745; ODC; OK/SW-cl.21; OPRT; UMPS
UniProt ID: (Human) P11172, (Mouse) P13439
Entrez Gene ID: (Human) 7372, (Mouse) 22247
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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